KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
6.97
Human Site:
S458
Identified Species:
9.58
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S458
E
N
L
P
K
D
I
S
E
E
D
I
K
T
V
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S458
E
N
L
P
K
D
I
S
E
E
D
I
K
T
V
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S456
P
R
E
N
L
V
K
S
G
N
E
I
L
N
L
Dog
Lupus familis
XP_532459
1267
140567
V442
R
E
N
L
P
K
D
V
S
E
E
E
V
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
E459
L
P
K
D
V
N
E
E
T
I
K
T
V
F
S
Rat
Rattus norvegicus
P46462
806
89330
R65
L
L
K
G
K
K
R
R
E
A
V
C
I
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
D423
P
R
E
K
L
P
K
D
V
D
E
E
D
V
R
Chicken
Gallus gallus
XP_418655
1290
143066
F466
E
D
D
V
K
C
A
F
S
A
W
L
K
D
S
Frog
Xenopus laevis
P23787
805
89193
R64
V
L
L
K
G
K
K
R
R
E
A
V
C
I
V
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
R65
L
L
K
G
K
K
R
R
E
T
V
C
I
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
R60
T
V
I
L
K
G
K
R
R
K
E
T
V
C
I
Honey Bee
Apis mellifera
XP_397107
1069
120490
E328
K
T
S
T
L
N
E
E
H
F
N
I
N
L
R
Nematode Worm
Caenorhab. elegans
P54812
810
89622
K69
S
V
I
L
K
G
K
K
R
R
E
T
V
S
I
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
T612
R
A
F
N
Q
W
L
T
C
V
S
C
M
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
C74
K
K
R
K
D
T
V
C
I
A
L
A
D
E
T
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
T302
H
L
W
D
A
F
F
T
H
P
M
N
G
A
K
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
N508
T
S
P
I
L
L
A
N
L
D
N
P
P
Y
L
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
13.3
6.6
N.A.
0
13.3
N.A.
0
20
20
13.3
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
26.6
13.3
N.A.
6.6
20
N.A.
13.3
33.3
26.6
20
N.A.
33.3
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
6
0
12
0
0
18
6
6
0
6
0
% A
% Cys:
0
0
0
0
0
6
0
6
6
0
0
18
6
6
0
% C
% Asp:
0
6
6
12
6
12
6
6
0
12
12
0
12
6
0
% D
% Glu:
18
6
12
0
0
0
12
12
24
24
30
12
0
6
0
% E
% Phe:
0
0
6
0
0
6
6
6
0
6
0
0
0
6
0
% F
% Gly:
0
0
0
12
6
12
0
0
6
0
0
0
6
0
0
% G
% His:
6
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
12
6
0
0
12
0
6
6
0
24
12
12
12
% I
% Lys:
12
6
18
18
42
24
30
6
0
6
6
0
18
6
6
% K
% Leu:
18
24
18
18
24
6
6
0
6
0
6
6
6
6
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% M
% Asn:
0
12
6
12
0
12
0
6
0
6
12
6
6
6
0
% N
% Pro:
12
6
6
12
6
6
0
0
0
6
0
6
6
0
0
% P
% Gln:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
12
6
0
0
0
12
24
18
6
0
0
0
0
12
% R
% Ser:
6
6
6
0
0
0
0
18
12
0
6
0
0
6
18
% S
% Thr:
12
6
0
6
0
6
0
12
6
6
0
18
0
12
12
% T
% Val:
6
12
0
6
6
6
6
6
6
6
12
6
24
18
18
% V
% Trp:
0
0
6
0
0
6
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _